Plastic Polymers for Efficient DNA Microarray Hybridization: Application to Microbiological Diagnostics
نویسندگان
چکیده
منابع مشابه
Plastic polymers for efficient DNA microarray hybridization : 1 Application to microbiological diagnostics
2 Fabrication of microarray devices using traditional glass slides is not easily 3 adaptable to integration into microfluidic systems. There is thus a need for the 4 development of polymeric materials showing a high hybridization signal to 5 background ratio enabling sensitive detection of microbial pathogens. We have 6 developed such plastic supports suitable for highly sensitive DNA microarra...
متن کاملPlastic polymers for efficient DNA microarray hybridization: application to microbiological diagnostics.
Fabrication of microarray devices using traditional glass slides is not easily adaptable to integration into microfluidic systems. There is thus a need for the development of polymeric materials showing a high hybridization signal-to-background ratio, enabling sensitive detection of microbial pathogens. We have developed such plastic supports suitable for highly sensitive DNA microarray hybridi...
متن کاملMicrobiological evaluation of acute periradicular abscesses by DNA-DNA hybridization.
OBJECTIVE The purpose of the present investigation was to examine the microbiota of acute periradicular abscesses of endodontic origin by using a molecular genetic method. STUDY DESIGN Pus was collected by aspiration from 27 cases diagnosed as acute abscesses of endodontic origin, and DNA was extracted to evaluate the occurrence of 49 bacterial species by using whole genomic DNA probes and ch...
متن کاملApplications of DNA microarray in disease diagnostics.
Rapid and accurate diagnosis of diseases is very important for appropriate treatment of patients. Recent advances in molecular-level interaction and detection technologies are upgrading the clinical diagnostics by providing new ways of diagnosis, with higher speed and accuracy. In particular, DNA microarrays can be efficiently used in clinical diagnostics which span from discovery of diseaserel...
متن کاملApplication of array-based comparative genomic hybridization to clinical diagnostics.
Microarray-based comparative genomic hybridization (array CGH) is a revolutionary platform that was recently adopted in the clinical laboratory. This technology was first developed as a research tool for the investigation of genomic alterations in cancer. It allows for a high-resolution evaluation of DNA copy number alterations associated with chromosome abnormalities. Array CGH is based on the...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Clinical Microbiology
سال: 2008
ISSN: 0095-1137,1098-660X
DOI: 10.1128/jcm.00377-08